Astbury Conversation 2018

On 17 April The PoPPI team took part in The Astbury Conversation Public Engagement Event with an interactive game titled ‘Protein-Matchmaking: How do proteins talk to one another, what happens when they miscommunicate and how do we deal with this through drug discovery?’

In a race against the clock, players ‘matched’ 3-D printed models of proteins to one another. If matched correctly, the proteins clicked together. The team also designed models of small-molecule inhibitors which fitted into pockets in the proteins, preventing them from fitting together.

This simple game allowed the team to demonstrate the complex principles of protein-protein interactions, and challenges for selective inhibition as pursued in the PoPPI programme in an effective way that could be understood by non-experts.

The Astbury Centre welcomed over 350 guests from all over the world to The Conversation which included fantastic talks including plenary speaker Nobel Laureate Prof Brian Kobilka.

More Public PoPPI Engagement